Complex Mathematics

Terra Oleo’s oil-producing microbes could replace destructive palm oil plantations


When most kids rebel against their families, they might become a ski bum, join a band, or go to art school. Shen Ming Lee decided to start a company.

“I grew up in the conventional palm oil industry,” Lee told TechCrunch. “My family’s business is one of the top producers in the palm oil space. And so I grew up a little bit — I have to admit —ashamed of what my family does.”

Palm oil has come to dominate the market for vegetable oils, with the raw ingredient and its derivatives appearing in everything from snack foods and cosmetics to pharmaceuticals and biofuels. But along the way, it has deforested vast swaths of the tropics, especially in Southeast Asia. 

The germ of Lee’s startup, Terra Oleo, emerged in 2022 when she met co-founder Boon Uranukul, who, as a doctoral candidate at MIT, had developed microbes that could produce building blocks of plastics using agricultural waste.

“I really had this desire to build something that was maybe going to build on my family’s legacy, but in a way that was more in line with my values as a Gen Z, sustainability-leading person,” Lee said. “We got thinking about what we could do differently, matching his expertise with my connections and strategic network.”

The Singapore-based startup has been operating in stealth for nearly two years to develop microbes that can transform agricultural waste into a variety of oils.

Terra Oleo has raised $3.1 million from ADB Ventures, Better Bite Ventures, Elev8.vc, The Radical Fund, a strategic corporate investor from the palm oil industry, and other investors, the startup exclusively told TechCrunch. Lee and Uranukul are also part of this year’s Breakthrough Energy Fellows cohort.

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Terra Oleo's founding team stand in a lab holding vials of oil.
Terra Oleo co-founders (from left): Min Hao Wong, PhD, Shen Ming Lee, and Boon Uranukul, PhD.Image Credits:Terra Oleo

Palm oil can be refined into dozens of derivatives, so Lee and Uranukul mapped them to determine where to begin. “What are the most high value ones? But also technologically, what’s easier for us to tackle and lower hanging fruit?” Lee said. 

“There’s the illusion that crude palm oil is the end all be all,” she said, adding that the raw ingredient is a “very low margin commodity.” Instead, they decided to skip straight to higher-value products, including cocoa butter and speciality oils used in the cosmetic and pharmaceutical industries.

To make those oils, the company selected three yeast species based on the microbes’ abilities to produce certain oils when fed with organic waste, including from agriculture and biodiesel production. It then used genetic and metabolic engineering to boost and tune their ability to produce certain fats and triglycerides.

Currently, the company is still in the lab, producing grams of oil at a time. But Lee said that Terra Oleo plans to use the funding to produce kilograms worth of the stuff. 

Already, Terra Oleo can produce oils for the cosmetic and pharmaceutical industries at costs far less than what they sell for. That’s mostly because the startup’s microbes produce the right chemical from the start, eliminating the need for pricey refining. 

“We’re looking at upwards of 80% margins for some of these specialty oleochemicals because they’re really expensive to produce conventionally,” Lee said.

Hitting the scale needed to replace significant amounts of palm oil won’t be easy. Last season, the world produced nearly 79 million metric tons, according to the USDA, though the market hasn’t grown significantly in the past six years.

For Lee, that’s an opportunity to show existing palm oil producers that maybe there’s another path.

“We’re not going to change from palm oil to other sources overnight,” she said. “It’s so prevalent, it’s such a versatile ingredient that I think it’s going to be a slow transition where we’re working with the industry to get to that diversified production mix that we want to see.”



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